product name：Human Cardiac Fibroblasts（人心臟成纖維細胞）；

cat no：ABC-TC3533；

Size/Quantity：1 vial；

Biosafety Level：1；

Shipping Info：Dry Ice；

Storage：Liquid Nitrogen；

Description：Human Cardiac Fibroblasts (HCFs,人心臟成纖維細胞) are isolated from heart tissue, providing structural support for cardiac myocytes. HCF is one of the major cellular components in the heart, participating in heart function, homeostasis, and structure. Cardiac fibroblast cells secrete collagen and play a role in providing structural support for the heart. The cardiac fibroblast cell proliferation and synthesis of matrix are vital to scar formation in myocardial infarction and cardiac fibrosis. However, inappropriate cardiac fibroblast proliferation is a causative factor in cardiac fibrosis.

After heart injury, some chemical signals like growth factors, cytokines, and matrikines are secreted in paracrine or autocrine manner. Those factors act on cardiac fibroblasts via changing fibroblast gene expression and boosting cell migration to the injured area, which then promote wound healing and scar formation.；

Quality Control：All cells test negative for mycoplasma, bacteria, yeast, and fungi；

Application：For research use only.