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Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. It binds to an intracellular pocket located within tyrosine kinases (TK).

色瑞替尼 Ceritinib Ceritinib, also known as LDK378, is a selective inhibitor of ALK1, a target found in metastatic non-small cell lung cancer (NSCLC).

克唑替尼 Crizotinib Crizotinib, also known as PF-02341066, is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors

厄洛替尼/埃羅替尼 Erlotinib Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor). Erlotinib HCl was approved.

Gefitinib, also known as ZD1839, is an anilinoquinazoline with antineoplastic activity. It inhibits the catalytic activity of numerous tyrosine kinases.